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Non-Oriental primary intrahepatic lithiasis: experience with 48 cases
Paulo Herman1, Telesforo Bacchella, Vincenzo Pugliese
1Department of Gastroenterology, University of São Paulo Medical School, R Eneas De Carvale Aguar, 255 São Paulo, Brazil. pherman@uol.com.br
World Journal of Surgery
|June 14, 2005
Summary
This study analyzed 48 Brazilian patients with non-Oriental primary intrahepatic lithiasis (PIHL). Personalized treatment led to good outcomes in 73.4% of cases, with unilateral stones faring better than bilateral.
Area of Science:
- Hepatology
- Gastroenterology
- Surgical Gastroenterology
Background:
- Non-Oriental primary intrahepatic lithiasis (PIHL) is a rare condition.
- Understanding its characteristics and treatment outcomes is crucial for patient management.
Purpose of the Study:
- To describe the diagnosis and treatment experience of non-Oriental PIHL in Brazilian patients.
- To analyze patient characteristics, treatment protocols, prognostic factors, and late results.
Main Methods:
- Retrospective analysis of 48 native Brazilian patients with symptomatic PIHL.
- Treatment strategies included liver resection for irreversible lesions and biliary drainage for bilateral stones.
- Evaluation of late results based on postoperative symptoms, pain recurrence, and cholangitis.
Main Results:
- Overall good late results were achieved in 73.4% of patients.
- Good results were observed in 94.1% of unilateral stone cases versus 62.1% of bilateral cases.
- Bilateral stones increased the risk of late complications 7.2-fold compared to unilateral stones.
Conclusions:
- Personalized treatment tailored to disease presentation is effective for non-Oriental PIHL.
- Despite rarity, patient characteristics resemble those of Oriental PIHL.
- The study highlights the importance of individualized surgical approaches for optimal outcomes.