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Updated: Aug 17, 2026

Optimizing Minimally Invasive Spine Surgery: A Fully 3D CT O-Arm Navigated Workflow in MIS TLIF
Published on: October 17, 2025
Minimally invasive spine surgery
J Alex Seldomridge1, Frank M Phillips
1Department of Orthopaedic Surgery, Rush University, Chicago, Illinois, USA.
Abstract:
This article reviews the rationale, suggested benefits, and techniques of minimally invasive surgery (MIS) of the spine. While the efficacy and outcomes of open spinal decompression and fusion procedures have been validated in numerous longitudinal studies, these surgeries typically involve significant soft-tissue dissection and muscle retraction. MIS techniques aim to minimize iatrogenic damage to the soft tissues around the spine while allowing surgeons to perform effective decompression and fusion procedures. Here we summarize the rationale for the trend toward spinal MIS and highlight the more common procedures.
Insights
Minimally invasive spine surgery (MIS) reduces tissue damage compared to open procedures. This review covers the reasons for MIS adoption and common techniques for spinal decompression and fusion.
Area of Science:
- Neurosurgery
- Orthopedic Surgery
- Spinal Surgery
Background:
- Open spinal surgery involves extensive soft-tissue dissection and muscle retraction.
- Established efficacy of open spinal decompression and fusion procedures.
- Need for less invasive surgical approaches to minimize patient trauma.
Purpose of the Study:
- To review the rationale behind the increasing adoption of minimally invasive surgery (MIS) for spinal procedures.
- To outline the suggested benefits of MIS compared to traditional open surgery.
- To describe the common techniques employed in spinal MIS.
Main Methods:
- Literature review of studies on spinal surgery techniques.
- Analysis of the rationale and benefits of minimally invasive approaches.
- Summary of prevalent minimally invasive spinal decompression and fusion procedures.
Main Results:
- Minimally invasive surgery (MIS) aims to decrease iatrogenic damage to spinal soft tissues.
- MIS allows for effective spinal decompression and fusion with reduced collateral injury.
- The trend towards spinal MIS is driven by its potential for improved patient outcomes and recovery.
Conclusions:
- Minimally invasive spine surgery (MIS) offers a less traumatic alternative to open surgery.
- Understanding MIS techniques is crucial for modern spinal surgical practice.
- Continued research and development in MIS are expected to further refine spinal interventions.

