Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Surface area and tissue volume increases with differential expansion.

M J Morykwas1, M W Marks, L C Argenta

  • 1Department of Plastic and Reconstructive Surgery, Bowman Gray School of Medicine, Winston-Salem, NC 27103.

Annals of Plastic Surgery
|April 1, 1992
PubMed
Summary

Differential tissue expanders create uneven tissue growth, leading to thinning in expanded areas. This study in pigs shows superior displacement, crucial for symmetrical breast reconstruction planning.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advances in hemangioma evaluation and treatment.

The Journal of craniofacial surgery·2006
Same author

Effects of varying levels of subatmospheric pressure on the rate of granulation tissue formation in experimental wounds in swine.

Annals of plastic surgery·2001
Same author

The use of vacuum-assisted closure therapy for the treatment of lower-extremity wounds with exposed bone.

Plastic and reconstructive surgery·2001
Same author

Vacuum-assisted closure for the treatment of degloving injuries.

Plastic and reconstructive surgery·2001
Same author

Treatment of soft tissue defects in pediatric patients using the V.A.C. system.

Clinical orthopaedics and related research·2000
Same author

Reconstruction of congenital chest wall deformities using solid silicone onlay prostheses.

Chest surgery clinics of North America·2000

Area of Science:

  • Plastic and reconstructive surgery
  • Biomedical engineering
  • Tissue engineering

Background:

  • Tissue expansion is crucial for reconstructive surgery, particularly for breast reconstruction.
  • Differential expanders aim to create asymmetrical tissue growth for specific anatomical needs.
  • Understanding tissue response to differential expansion is vital for optimizing outcomes.

Purpose of the Study:

  • To evaluate the volumetric and dimensional changes in soft tissue using differential expanders in a preclinical model.
  • To assess the impact of differential expansion on tissue thickness and surface area.
  • To investigate the displacement patterns of differential expanders during inflation.

Main Methods:

  • Differential expanders were implanted in the rib area of a pig model.

Related Experiment Videos

  • A grid system was used to measure surface area, thickness, and calculate volume changes in tissue subunits.
  • Expander inflation and subsequent tissue measurements were performed over time.

    • Main Results:

    • Areas of preferential expansion showed the greatest surface area increase but also significant thinning.
    • While tissue volume increased, the volumetric gain was less pronounced than the surface area expansion.
    • Differential expanders consistently displaced superiorly during the inflation process.

    Conclusions:

    • Differential expansion leads to a trade-off between surface area gain and tissue thickness, with thinning occurring in highly expanded zones.
    • The superior displacement of differential expanders is a critical factor to consider in surgical planning.
    • Anticipating expander displacement is essential for achieving symmetrical inframammary folds in breast reconstruction.