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An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
Published on: September 12, 2019
Primary hepatic carcinoid tumor
W Bastaki1, F Mothaffer, J Varro
1Liver Surgery Unit, Mubarak Al-Kabeer Hospital, Kuwait.
Summary
This case study details a rare primary carcinoid tumor of the liver. Treatment with liver dearterialization provided effective palliation for this inoperable carcinoid tumor.
Area of Science:
- Hepatobiliary surgery
- Surgical oncology
- Gastroenterology
Background:
- Primary carcinoid tumors of the liver are exceptionally rare, posing diagnostic and therapeutic challenges.
- This report focuses on a unique case of an inoperable primary hepatic carcinoid tumor.
Observation:
- A 44-year-old male presented with a large, inoperable liver mass diagnosed as carcinoid tumor via fine needle aspiration cytology.
- Extensive investigations, including laparotomy and intraoperative ultrasound, failed to identify a primary gastrointestinal or pancreatic source.
- The patient underwent percutaneous embolization and complete liver dearterialization, which appeared to control tumor growth.
Findings:
- Complete dearterialization of the liver was performed for a primary, inoperable hepatic carcinoid tumor.
- The intervention successfully halted tumor progression and offered significant palliation.
Implications:
- Liver dearterialization can be an effective palliative strategy for managing inoperable primary carcinoid tumors of the liver.
- This approach may offer long-term stability and improved quality of life in select patients with rare hepatic malignancies.
