Persistent photosensitivity following occupational exposure to epoxy resin

Persistent photosensitivity developed in eight men following occupational exposure to hot epoxy resin fumes. The condition was limited to sites the resin contacted. Small doses of ultraviolet-A light (2 to 5 joules/sq cm) evoked abnormal reactions consisting of erythema, edema, and papules in the clinically involved skin. Positive photopatch tests to epoxy resin were observed in four subjects, and to 4, 4'-isopropylidenediphenol (Bisphenol A) in all. The photosensitivity is most probably due to photocontact allergy to 4,4'-isopropylidenediphenol or to a closely related chemical.