Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

You are what you eat.

Sonalee Kulkarni1, Andrew G Lee, Sarah A Holstein

  • 1Department of Ophthalmology, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242-1091, USA.

Survey of Ophthalmology
|June 22, 2005
PubMed
Summary

Wernicke encephalopathy, a condition from thiamine deficiency, presents with eye movement issues, poor coordination, and confusion. Patients who have undergone gastric bypass surgery are a newly identified risk group, showing significant improvement with thiamine treatment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Apraxia of lid opening in multiple sclerosis.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2022
Same author

Sphenoid Sinusitis-Associated Optic Neuropathy: A Forgotten Disease.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2022
Same author

Posterior Ischemic Optic Neuropathy Following Recurrent COVID-19 in Prior Bilateral Sequential Nonarteritic Anterior Ischemic Optic Neuropathy.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2022
Same author

Optic nerve sheath diameter and spaceflight: defining shortcomings and future directions.

NPJ microgravity·2022
Same author

Progressive Optic Neuropathy in Cerebellar Ataxia, Areflexia, Optic Atrophy, and Sensorineural Hearing Loss Syndrome: The Importance of Targeted Gene Testing.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2022
Same author

Visual Loss as the Presenting Manifestation of Leptomeningeal Spread of Glioblastoma Multiforme to the Optic Chiasm.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2022

Area of Science:

  • Neurology
  • Nutritional Science

Background:

  • Wernicke encephalopathy is a serious neurological condition characterized by ophthalmoplegia, ataxia, and altered mental status.
  • It stems from thiamine (vitamin B1) deficiency, often associated with chronic alcoholism.

Observation:

  • While commonly linked to alcoholism, Wernicke encephalopathy is increasingly recognized in patients undergoing gastric bypass surgery for morbid obesity.
  • Ocular manifestations, including florid papilledema and optic neuropathy, though less common, can be present.

Findings:

  • The study highlights gastric bypass patients as a potential new demographic at risk for Wernicke encephalopathy.
  • Prompt thiamine replacement is crucial for recovery, often leading to dramatic clinical improvement.

Implications:

Related Experiment Videos

  • Increased awareness is needed to identify Wernicke encephalopathy in post-gastric bypass patients.
  • Early diagnosis and intervention with thiamine are critical to prevent irreversible neurological damage and ensure patient recovery.