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PSF-choice: a novel MRI method for shaping point-spread functions in phase-encoding dimensions.

Lawrence P Panych1, Lei Zhao, Robert V Mulkern

  • 1Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. panych@bwh.harvard.edu

Magnetic Resonance in Medicine
|June 22, 2005
PubMed
Summary

A new imaging method, PSF-Choice, effectively eliminates ringing artifact in spectroscopic imaging by controlling the point-spread function (PSF). This technique maintains spatial resolution and signal-to-noise ratio, proving feasible in phantom experiments.

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Area of Science:

  • Magnetic Resonance Imaging
  • Image Reconstruction
  • Spectroscopic Imaging

Background:

  • Ringing artifact is a significant problem in phase-encoding imaging, especially when few phase encodes are acquired.
  • Standard phase-encoding methods can lead to undesirable side lobes in the point-spread function (PSF).
  • Spectroscopic imaging often requires minimal phase encoding, exacerbating artifact issues.

Purpose of the Study:

  • To introduce and validate a novel imaging method, PSF-Choice, for arbitrary point-spread function (PSF) control.
  • To demonstrate the capability of PSF-Choice in mitigating ringing artifact in phase-encoding dimensions.
  • To assess the impact of PSF-Choice on spatial resolution, signal-to-noise ratio (SNR), and temporal resolution.

Main Methods:

  • PSF-Choice utilizes partial 2D radiofrequency (RF) excitations to generate aliased excitations.

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  • These aliased excitations are then encoded using conventional phase-encoding gradients.
  • The PSF of the reconstructed image is theoretically determined by the RF excitation profile.

    • Main Results:

    • Simulations show that PSF-Choice can achieve a Gaussian-like PSF, effectively eliminating side lobes and associated ringing artifact.
    • The method does not adversely affect spatial resolution or signal-to-noise ratio (SNR) compared to standard phase encoding.
    • Temporal resolution is maintained as the number of required encodes remains the same.

    Conclusions:

    • PSF-Choice offers a viable solution for eliminating ringing artifact in phase-encoding imaging, particularly in applications like spectroscopic imaging.
    • The method demonstrates the potential to improve image quality without compromising key imaging performance metrics.
    • Initial phantom experiments confirm the feasibility of PSF-Choice in artifact reduction.