Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fluid in the flute: Reversible hydromyelia.

Tim Wehner1, Jeffrey S Ross, Richard M Ransohoff

  • 1The Cleveland Clinic Foundation, Department of Neurology-S 90, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

Journal of the Neurological Sciences
|June 24, 2005
PubMed
Summary

Syrinx formation, a complication of demyelinating disease, can be reversible. This study shows a syrinx in acute transverse myelitis resolved within six months, offering new hope for patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

From Sequencing to Treatment: Operational Challenges in Translating Precision Oncology Into Clinical Practice.

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting·2026
Same author

Neoadjuvant Sacituzumab Govitecan in Patients With Muscle-Invasive Bladder Cancer: Primary Results of the SURE-01 Trial.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026
Same author

Ultra-high tumor mutation burden breast cancer: genomic profiling and real-world immunotherapy results.

NPJ breast cancer·2026
Same author

Homozygous Loss of Recombination Repair Genes and Poly ADP-Ribose Polymerase Inhibitor Benefit for Patients With Ovarian Cancer.

JCO precision oncology·2026
Same author

Genomics of <i>MTAP</i> Loss in >500,000 Solid Tumor Specimens Profiled Using Comprehensive Genomic Profiling Platforms.

JCO precision oncology·2026
Same author

Diabetic striatopathy associated with nonketotic hyperglycemia.

JCEM case reports·2026

Area of Science:

  • Neurology
  • Neuroimmunology
  • Spinal Cord Medicine

Background:

  • Demyelinating diseases can lead to the formation of non-communicating syrinxes.
  • The reversibility of syrinx formation in this context remains poorly understood.
  • Previous reports document syrinx formation in approximately 50 patients with demyelinating disease.

Observation:

  • A patient diagnosed with acute transverse myelitis developed a syrinx.
  • The syrinx was monitored over a six-month period.
  • Complete resolution of the syrinx was observed within this timeframe.

Findings:

  • This case demonstrates that syrinx formation associated with demyelinating disease, specifically acute transverse myelitis, can be a reversible phenomenon.
  • The observed resolution challenges the assumption of permanence for these spinal cord lesions.

Related Experiment Videos

  • The study provides evidence for potential recovery from syrinx-induced neurological deficits.

    • Implications:

    • Suggests that therapeutic strategies targeting demyelination may influence syrinx resolution.
    • Highlights the importance of monitoring for syrinx development and resolution in patients with demyelinating conditions.
    • Opens avenues for further research into the mechanisms underlying syrinx formation and regression in the central nervous system.