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Related Experiment Videos

Initial experience with the Abiomed AB5000 ventricular assist device system.

Louis E Samuels1, Elena C Holmes, Phil Garwood

  • 1Department of Cardiothoracic Surgery, Lankenau Hospital, Wynnewood, Pennsylvania 19096, USA. samuelsle@aol.com

The Annals of Thoracic Surgery
|June 25, 2005
PubMed
Summary

The Abiomed AB5000 ventricular assist device (VAD) offers versatile paracorporeal pneumatic support. Initial use showed potential for hemolysis and lower flows, suggesting areas for device optimization.

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Area of Science:

  • Cardiovascular Surgery
  • Medical Devices
  • Mechanical Circulatory Support

Background:

  • The Abiomed AB5000 is a Food and Drug Administration-approved ventricular assist device (VAD) for short-to-intermediate term use.
  • It features a vacuum-assisted console and a pneumatically driven paracorporeal blood pump, compatible with BVS5000 or AB5000 pumps.

Observation:

  • The study evaluated four cases using the AB5000 VAD, with two placed de novo and two transitioned from BVS5000 systems.
  • Hemolysis was noted in two cases, associated with high-velocity jets from the inflow cannula observed via echocardiography.
  • AB5000 VAD flows averaged 4.0-4.5 L/min, slightly lower than the BVS5000 system.

Findings:

  • The AB5000 VAD demonstrated versatility, allowing de novo placement or transition from BVS5000 without additional surgery.

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  • Two patients experienced hemolysis, linked to inflow cannula characteristics.
  • Patient outcomes included one death from multiorgan failure, two successful weans to long-term care, and one successful discharge home.

    • Implications:

    • The AB5000 VAD is a viable option for paracorporeal pneumatic circulatory support.
    • Potential for hemolysis and lower flow rates necessitates further investigation and potential modifications.
    • Optimizing cannula design, placement, and console settings may enhance AB5000 VAD performance and patient outcomes.