Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

525
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
525
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

414
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
414
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

955
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
955
Aortic Regurgitation IV: Nursing Management01:17

Aortic Regurgitation IV: Nursing Management

367
A nurse managing a patient with aortic regurgitation begins with a comprehensive assessment, including a review of the patient's medical history, family history, and lifestyle factors. During the cardiac examination, the nurse listens for heart sounds and checks for signs of valve abnormalities. The nurse also observes for symptoms such as dyspnea, orthopnea, and paroxysmal nocturnal dyspnea and assesses the patient's endurance and daily activity tolerance.Based on the findings, the nurse...
367

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prosthesis-Patient Mismatch in All-Comer Patients Undergoing Newer-Generation Self-Expanding Transcatheter Aortic Valve Replacement.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions·2026
Same author

Robotically-assisted, totally endoscopic myocardial bridge unroofing: surgical technique.

Journal of visualized surgery·2026
Same author

Long-term outcomes of postoperative atrial fibrillation after cardiac surgery: Results from 19,000 patients.

The Journal of thoracic and cardiovascular surgery·2026
Same author

Balloon Pulmonary Angioplasty for Treatment of Chronic Thromboembolic Pulmonary Hypertension: Statement From the BPA-CTEPH Alliance.

JACC. Cardiovascular interventions·2026
Same author

Impact of Prosthesis-Patient Mismatch After Surgical Mitral Valve Replacement: Systematic Review and Meta-Analysis.

The American journal of cardiology·2026
Same author

Arch-first approach in total arch reconstruction: The Pittsburgh experience.

JTCVS techniques·2026

Related Experiment Video

Updated: Mar 6, 2026

Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement
09:57

Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement

Published on: January 20, 2022

3.2K

Oversizing Transcatheter Aortic Valves: Are We Getting It Right?

Takuya Ogami1, Abbad Sultan2, Xander Jacquemyn2

  • 1UPMC Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania.

The American Journal of Cardiology
|March 4, 2026
PubMed
Summary

Optimal valve sizing in transcatheter aortic valve replacement (TAVR) is crucial. Moderate oversizing (10-20%) of the aortic valve is linked to reduced mortality without increasing early complications.

Keywords:
pacemaker implantationparavalvular leaksizingtranscatheter aortic valve implantationtranscatheter heart valve

More Related Videos

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.9K
Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
06:04

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation

Published on: August 8, 2025

667

Related Experiment Videos

Last Updated: Mar 6, 2026

Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement
09:57

Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement

Published on: January 20, 2022

3.2K
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.9K
Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
06:04

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation

Published on: August 8, 2025

667

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Medical Devices

Background:

  • Optimal valve sizing is critical for successful transcatheter aortic valve replacement (TAVR).
  • Oversizing the transcatheter heart valve impacts patient outcomes and procedural success.

Purpose of the Study:

  • To evaluate the association between different degrees of transcatheter aortic valve oversizing and patient outcomes after TAVR.
  • To determine if moderate oversizing (10-20%) is associated with improved mortality or complications.

Main Methods:

  • Retrospective analysis of 1,808 patients undergoing TAVR from 2010-2025.
  • Patients categorized into minimal (<10%), moderate (10-20%), and severe (≥20%) oversizing groups.
  • Multivariable analysis used to assess outcomes including all-cause mortality and early complications.

Main Results:

  • No significant differences in early outcomes (e.g., stroke, pacemaker implantation) across oversizing groups.
  • Moderate oversizing (10-20%) was independently associated with lower all-cause mortality (HR=0.63; p=0.02).
  • Severe oversizing (≥20%) showed no significant difference in all-cause mortality compared to minimal oversizing.

Conclusions:

  • A moderate oversizing range of 10-20% for transcatheter aortic valves is associated with reduced all-cause mortality.
  • This moderate oversizing range did not increase early procedural complications or paravalvular leak.
  • Findings suggest a potential benefit of moderate oversizing in TAVR for long-term survival.