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[Nasal leishmaniasis: a case report].

J-Fr Vellin1, M Russier, G Mougeot

  • 1Service d'ORL et Chirurgie Cervico-Faciale, Centre Hospitalier Universitaire de Clermont-Ferrand, BP 69, 63003, Clermont-Ferrand Cedex 1.

Annales D'Oto-Laryngologie Et De Chirurgie Cervico Faciale : Bulletin De La Societe D'Oto-Laryngologie Des Hopitaux De Paris
|June 25, 2005
PubMed
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A septal perforation biopsy successfully diagnosed nasal leishmaniasis in a woman with cirrhosis. Treatment led to lesion regression and improved liver function, highlighting biopsy

Area of Science:

  • Otorhinolaryngology
  • Infectious Diseases
  • Parasitology

Background:

  • Nasal leishmaniasis is a rare parasitic infection presenting diagnostic challenges.
  • Septal perforations can manifest with diverse symptoms, including rhinosinusitis and vestibulitis.
  • Cirrhosis may influence the presentation and management of infectious diseases.

Observation:

  • A 54-year-old woman with cirrhosis presented with a septal perforation, crusty rhinosinusitis, and nasal vestibulitis.
  • Initial biological and radiological findings were unremarkable.

Findings:

  • A mucocartilaginous biopsy of the septal perforation confirmed mucosal leishmaniasis.
  • Anti-parasitic treatment resulted in the regression of both the mucocutaneous lesion and hepatic insufficiency.

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Implications:

  • Biopsy of septal perforations is a valuable diagnostic method for differentiating various nasal pathologies.
  • Leishmaniasis should be considered in the differential diagnosis of complex rhinologic conditions.
  • This case underscores the potential systemic impact of leishmaniasis and the effectiveness of targeted treatment.