[Genetic polymorphisms of human short tandem repeat vWA]
Yi Li1, Bing-tao Hao, Yan-li Yang
1Genetics Department,the People's Hospital of Henan Province, Zhengzhou 450003, China.
Abstract:
We researched the genetic polymorphisms of vWA in Henan population and its usefulness in forensic science.DNA extracted from non-relative persons in Henan population with Chelex was amplified by polymerase chain reaction and was typed by nondenaturing polyacrylamide gel electrophoresis silver staining.A total of 8 alleles and 19 genotypes were found in Henan population,its heterozygosity is high and the locus can be used in forensic genetics. We obtained the allelic frequency of the locus vWA in Henan population. The results of amniotic fluid,villus,blood stain indicate vWA is a good locus for forensic study.
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