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Related Experiment Videos

EVAcon: a protein contact prediction evaluation service.

Osvaldo Graña1, Volker A Eyrich, Florencio Pazos

  • 1Protein Design Group, Centro Nacional de Biotecnologia (CNB-CSIC) Cantoblanco, 28049 Madrid, Spain.

Nucleic Acids Research
|June 28, 2005
PubMed
Summary
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EVAcon is a new automated web service that evaluates protein contact prediction servers. It provides precise comparisons using common protein subsets and CASP criteria for continuous performance assessment.

Area of Science:

  • Computational biology
  • Bioinformatics
  • Structural biology

Background:

  • Contact prediction is crucial for determining protein structure.
  • Evaluating the performance of prediction servers is essential for scientific advancement.
  • Existing evaluation methods may lack continuous monitoring or standardized comparison.

Purpose of the Study:

  • To introduce EVAcon, an automated web service for evaluating protein contact prediction servers.
  • To provide a standardized and continuous method for assessing server performance.
  • To facilitate precise comparisons of different contact prediction servers.

Main Methods:

  • EVAcon monitors nine contact and general structure prediction servers.
  • It compares server results against newly determined experimental structures from the Protein Data Bank (PDB).

Related Experiment Videos

  • Evaluation uses common protein subsets and criteria aligned with the CASP assessment.

    • Main Results:

    • EVAcon continuously evaluates server performance.
    • It enables precise comparisons based on standardized criteria.
    • The service monitors both specialized and general structure prediction servers.

    Conclusions:

    • EVAcon offers a valuable tool for the continuous evaluation of protein structure prediction servers.
    • The service enhances the reliability and comparability of contact prediction methods.
    • EVAcon contributes to the ongoing improvement of protein structure prediction technologies.