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Updated: Aug 17, 2026

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
Published on: February 4, 2018
[Cardiac abnormalities of lyme borreliosis]
P Bartůnĕk1, K Gorican, V Mrázek
1IV. interní klinika 1. LF UK a VFN, Praha. petr.bartunek@lf1.cuni.cz
Insights
Lyme borreliosis can cause cardiac issues like Lyme carditis. This study investigates cardiac abnormalities in patients treated for early Lyme disease, specifically erythema migrans.
Area of Science:
- Infectious Diseases
- Cardiology
- Epidemiology
Context:
- Lyme borreliosis, a tick-borne illness, presents diverse clinical manifestations.
- Cardiac involvement, known as Lyme carditis, poses diagnostic challenges due to varied presentations.
- Early Lyme disease, particularly erythema migrans, requires thorough investigation for potential long-term complications.
Purpose:
- To review the fundamental characteristics, incidence, epidemiology, pathogenesis, and clinical presentation of Lyme borreliosis.
- To specifically examine cardiac abnormalities associated with Lyme borreliosis, including Lyme carditis.
- To present original research on Borrelia-induced dilated cardiomyopathy and a prospective study on cardiac outcomes after early antibiotic treatment for erythema migrans.
Summary:
- The article provides a comprehensive overview of Lyme borreliosis, emphasizing its cardiac manifestations.
- It reviews existing literature on Lyme carditis, highlighting diagnostic difficulties.
- The authors present their experience with Borrelia-related dilated cardiomyopathy and a prospective study assessing cardiac abnormalities in patients treated for early erythema migrans.
Impact:
- This research contributes to understanding the long-term cardiac sequelae of Lyme borreliosis, even after appropriate early treatment.
- It underscores the importance of monitoring patients for cardiac complications following Lyme disease.
- Findings may inform clinical guidelines for managing Lyme borreliosis and its potential cardiovascular impact.
Abstract:
The article summarizes basic characteristics of Lyme borreliosis, its incidence, epidemiology, pathogenesis and clinical image. Particular attention is given to the review of papers aimed at the cardiac abnormalities--the Lyme carditis. Though they are not very frequent, due to the variability of their clinical course and due to various forms, which are difficult to diagnose, they can represent a specific problem. Major part of the article is given to the authors' own experience with the dilated cardiomyopathy of the Borrelia origin and namely to the perspective study of the patients after the skin form of the disease erythema migrans, who were treated "lege artis" in the early phase of the disease with antibiotics. Authors were interested how many of those patients would develop later the cardiac abnormalities.
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