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Apoplast-Extraction Based Method to Improve the Purity of Plant Produced Recombinant Protein
Published on: July 5, 2024
Commercialization of plant-based vaccines from research and development to manufacturing
1Biotechnology Institute, 5819 Stallion Ridge, College Station, TX 77845, USA. jhoward999@appliedbiotech.org
Abstract:
The benefits of using plant-based oral vaccines are discussed. Transgenic maize expressing an antigen of transmissible gastroenteritis virus (TGEV) is reported as a model to demonstrate efficacy. Young pigs that were fed the TGEV corn orally were protected against challenge with virulent TGEV. Additional parameters important in providing a reliable and consistent supply of plant-based vaccines are discussed. Finally, vaccines developed in maize are evaluated for their potential to contaminate either the food supply or the environment.
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