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[Cardiovascular effects of kainic acid injected into habenular nucleus]
1Department of Physiology, Norman Bethune University of Medical Sciences, Changchun, China.
The present study was to determine if the cardiovascular effect being produced by exciting cells in the habenular nucleus (Hab). Experiments were performed on urethane-anesthetized rats. Microinjection of kainic acid into Hab demonstrated dose-dependent increases in arterial blood pressure and heart rate, accompanied by other sympathetic reactions, such as mydriasis and pilo-erection. But microinjection of lidocaine into Hab did not elicit similar effects mentioned above.
The present study was to determine if the cardiovascular effect being produced by exciting cells in the habenular nucleus (Hab). Experiments were performed on urethane-anesthetized rats. Microinjection of kainic acid into Hab demonstrated dose-dependent increases in arterial blood pressure and heart rate, accompanied by other sympathetic reactions, such as mydriasis and pilo-erection. But microinjection of lidocaine into Hab did not elicit similar effects mentioned above.