Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Photosensitivity to exogenous agents.

Lela Lankerani1, Elma D Baron

  • 1Department of Dermatology, Case Western Reserve University, Cleveland, Ohio 44106, USA. lelalanky@hotmail.com

Journal of Cutaneous Medicine and Surgery
|July 1, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Patient-reported satisfaction, comfortability, and efficacy of home phototherapy.

Photodermatology, photoimmunology & photomedicine·2022
Same author

The Effect of Shift Work and Poor Sleep on Self-Reported Skin Conditions: A Survey of Call Center Agents in the Philippines.

Clocks & sleep·2020
Same author

The Immune System and Pathogenesis of Melanoma and Non-melanoma Skin Cancer.

Advances in experimental medicine and biology·2020
Same author

Comparison of racial distribution of photodermatoses in USA academic dermatology clinics: A multicenter retrospective analysis of 1080 patients over a 10-year period.

Photodermatology, photoimmunology & photomedicine·2020
Same author

Topical application of ST266 reduces UV-induced skin damage.

Clinical, cosmetic and investigational dermatology·2017
Same author

PEGylated Dendrimers as Drug Delivery Vehicles for the Photosensitizer Silicon Phthalocyanine Pc 4 for Candidal Infections.

Biomacromolecules·2017
Same journal

'Cockade' or 'Targetoid' Variant of Syphilis.

Journal of cutaneous medicine and surgery·2026
Same journal

Tinea Imbricata.

Journal of cutaneous medicine and surgery·2026
Same journal

Intergenerational Clouston Syndrome.

Journal of cutaneous medicine and surgery·2026
Same journal

Herpes Zoster Ophthalmicus-Associated Trigeminal Trophic Syndrome.

Journal of cutaneous medicine and surgery·2026
Same journal

Borderline Lepromatous Leprosy Presenting Solely as a Nasal Plaque.

Journal of cutaneous medicine and surgery·2026
Same journal

Efficacy and Safety of Topical 1.5% Ruxolitinib for Chronic Hand Eczema in Real‑World Practice.

Journal of cutaneous medicine and surgery·2026
See all related articles

Cutaneous photosensitivity reactions, including phototoxic and photoallergic responses, are common. Identifying and avoiding the causative agent (chemical or light) is key, alongside protective clothing and high SPF sunscreen.

Area of Science:

  • Dermatology
  • Photobiology

Background:

  • Cutaneous photosensitivity reactions are adverse responses to UV radiation.
  • These reactions can be phototoxic or photoallergic, triggered by exogenous chemicals.

Purpose of the Study:

  • To review the etiologic factors, clinical characteristics, pathogenesis, and treatment of cutaneous photosensitivity reactions.

Main Methods:

  • A literature review was conducted on articles discussing phototoxic and photoallergic reactions.
  • Information on photoinduced reactions and their treatment was synthesized.

Main Results:

  • Phototoxic reactions result from UV radiation interacting with chemicals like amiodarone, retinoids, NSAIDs, diuretics, and antibiotics.
  • Photoallergic reactions are caused by substances such as fragrances, sunscreens, topical antimicrobials, NSAIDs, and psychiatric medications.

Related Experiment Videos

  • Phototoxic and photoallergic reactions are distinct based on pathogenesis, clinical presentation, and histology.

    • Conclusions:

    • Photoinduced reactions from exogenous chemicals are prevalent skin conditions.
    • Effective treatment involves identifying and eliminating the offending photosensitizing agent or light exposure.
    • Protective measures include UV-protective clothing and high-SPF sunscreens for unavoidable light exposure.