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Updated: Dec 9, 2025

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
Published on: September 7, 2013
The Immune System and Pathogenesis of Melanoma and Non-melanoma Skin Cancer
Kory P Schrom1, InYoung Kim2,3, Elma D Baron2,3,4
1Department of Dermatology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA. kory.schrom@uhhospitals.org.
Abstract:
Tumor development is the result of genetic derangement and the inability to prevent unfettered proliferation. Genetic derangements leading to tumorigenesis are variable, but the immune system plays a critical role in tumor development, prevention, and production. In this chapter, we will discuss the importance of the immune system as it relates to the development of skin cancer-both melanoma and non-melanoma skin cancers (NMSC).
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