Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neurogenesis and depression.

T D Perera1, S H Lisanby

  • 1New York State Psychiatric Institute and Columbia University College of Physicians and Surgeons, USA.

Journal of Psychiatric Practice
|July 2, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Older adults benefit from more widespread brain network integration during working memory.

NeuroImage·2020
Same author

Online repetitive transcranial magnetic stimulation during working memory in younger and older adults: A randomized within-subject comparison.

PloS one·2019
Same author

Complementary topology of maintenance and manipulation brain networks in working memory.

Scientific reports·2018
Same author

Comparison of electric field strength and spatial distribution of electroconvulsive therapy and magnetic seizure therapy in a realistic human head model.

European psychiatry : the journal of the Association of European Psychiatrists·2016
Same author

Improvement in quality of life with left prefrontal transcranial magnetic stimulation in patients with pharmacoresistant major depression: acute and six month outcomes.

Brain stimulation·2013
Same author

Separating hope from hype: some ethical implications of the development of deep brain stimulation in psychiatric research and treatment.

CNS spectrums·2010
Same journal

Pharmacy of the Mind: The Uncanny Origins of Psychiatric Drugs, and The World That Shaped Them.

Journal of psychiatric practice·2026
Same journal

Commentary on the Risks of Prescription GLP-1 Agonists in Patients on Psychiatric Medications.

Journal of psychiatric practice·2026
Same journal

A Case of GLP-1 Receptor Agonist-Induced Lithium Neurotoxicity.

Journal of psychiatric practice·2026
Same journal

A Case of GLP-1 Receptor Agonist-Induced Dysphoria and Aggression in a Patient With Underlying Major Depressive Disorder.

Journal of psychiatric practice·2026
Same journal

Dispositional Mindfulness and Perceived Stress in Psychiatric and Nonpsychiatric Physicians: A Facet-level Pilot Study.

Journal of psychiatric practice·2026
Same journal

Prescribing Under Pressure: History and Legal Insights Into Boxed Warnings for Psychotropic Drugs.

Journal of psychiatric practice·2026
See all related articles

New brain cell generation (neurogenesis) continues into adulthood and is impacted by depression. Antidepressant treatments may help by stimulating this crucial neurogenesis process.

Area of Science:

  • Neuroscience
  • Neurobiology

Background:

  • Adult neurogenesis, the generation of new neurons in the adult brain, is a significant area of neuroscience.
  • Factors like stress and neurotransmitter imbalances can impair neurogenesis, potentially contributing to depression.
  • Morphological brain changes associated with depression may be linked to reduced neurogenesis.

Purpose of the Study:

  • To review current literature on adult neurogenesis.
  • To explore the relationship between neurogenesis and the pathogenesis of major depression.
  • To discuss the potential role of antidepressant treatments in modulating neurogenesis for depression therapy.

Main Methods:

  • Literature review of recent studies on neurogenesis and depression.
  • Analysis of neurobiological models of depression.

Related Experiment Videos

  • Examination of evidence for antidepressant effects on neurogenesis.

    • Main Results:

    • Adult neurogenesis is a recognized phenomenon with implications for brain function.
    • Dysregulation of neurogenesis is implicated in the pathophysiology of major depression.
    • Emerging evidence suggests that antidepressants may promote neurogenesis.

    Conclusions:

    • Neurogenesis is a key factor in understanding and potentially treating major depression.
    • Targeting neurogenesis represents a promising therapeutic strategy for depression.
    • Further research into neurogenesis modulation is warranted for depression treatment development.