Related Experiment Video
Updated: Aug 17, 2026

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection
Published on: August 11, 2023
Metastatic breast cancer of the oral cavity
Robert Todd Adelson1, Robert J DeFatta, Brett A Miles
1Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, USA.
Objective:
To present a rare case of breast carcinoma initially presenting as an oral cavity mass.
Study Design:
Case report with review of the literature.
Results:
A case is presented of a postmenopausal woman with a remote history of treated breast carcinoma who was declared disease-free 2 years before presentation. She presented with an enlarging vestibule mass consistent with metastatic breast carcinoma. Subsequent investigations revealed widely metastatic disease for which the patient was referred for palliative chemotherapy.
Conclusions:
Metastatic disease to the oral cavity represents only 1% of all oral cavity malignancies. A high index of clinical suspicion is necessary when evaluating patients with a history of non-head and neck carcinoma.
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