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Related Concept Videos

Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Disorders of Hemostasis01:24

Disorders of Hemostasis

Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
The ABO Blood Group01:12

The ABO Blood Group

The ABO blood group system is a critical element of transfusion medicine, essential for determining blood compatibility in transfusions and organ transplants. It is based on specific antigens, or agglutinogens, present on the surface of red blood cells (RBCs) and corresponding antibodies, or agglutinins, in the blood plasma.
Antigens in the ABO Blood Group System
Antigens are substances that can trigger an immune response, leading to the production of antibodies. In the ABO blood group system,...
Blood Typing01:10

Blood Typing

Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target antigens A,...
Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...

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Antigens Protected Functional Red Blood Cells By The Membrane Grafting Of Compact Hyperbranched Polyglycerols
11:31

Antigens Protected Functional Red Blood Cells By The Membrane Grafting Of Compact Hyperbranched Polyglycerols

Published on: January 2, 2013

Blood management: issues and options.

John J Callaghan1, Michael R O'Rourke, Steve S Liu

  • 1Department of Orthopedics and Rehabilitation, University of Iowa, 01029 JPP, Iowa City, IA 52242, USA.

The Journal of Arthroplasty
|July 2, 2005
PubMed
Summary
This summary is machine-generated.

Perioperative blood management for total joint arthroplasty has advanced significantly. Patient-specific strategies, considering hemoglobin and comorbidities, now offer cost-effective care with reduced morbidity.

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Area of Science:

  • Orthopedic Surgery
  • Anesthesiology
  • Transfusion Medicine

Background:

  • Perioperative blood management in total joint arthroplasty (TJA) has undergone substantial evolution over 30 years.
  • Understanding of blood loss and replacement options in TJA patients has improved.
  • Traditional approaches are shifting towards more individualized care.

Purpose of the Study:

  • To review the evolution of blood management strategies in TJA.
  • To highlight the development and impact of patient-specific blood management programs.
  • To assess the efficacy and cost-effectiveness of modern blood management in TJA.

Main Methods:

  • Review of literature on perioperative blood management in TJA over the past three decades.
  • Analysis of changing strategies based on updated knowledge of blood loss and transfusion.
  • Examination of patient-specific protocols incorporating preoperative hemoglobin, comorbidities, and anticipated blood loss.

Main Results:

  • Blood management strategies have shifted from general protocols to tailored patient approaches.
  • Patient-specific blood management programs have been developed and validated.
  • These programs demonstrate cost-efficiency and contribute to low patient morbidity.

Conclusions:

  • Modern perioperative blood management in TJA is increasingly personalized.
  • Patient-specific strategies optimize care by accounting for individual patient factors.
  • These tailored programs lead to improved outcomes, including reduced morbidity and cost savings.