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Updated: Aug 16, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Geographic information system localization of community-acquired MRSA soft tissue abscesses
Michael V Tirabassi1, George Wadie, Kevin P Moriarty
1Division of Pediatric Surgery, Baystate Medical Center Children's Hospital, Tufts University School of Medicine, Springfield, MA 01103, USA.
Background:
Soft tissue infections with methicillin-resistant Staphylococcus aureus (MRSA) pose an ever-increasing risk to children in the community. Although historically these infections were limited to children with prolonged hospitalization, the authors have seen an increase in community-acquired infections in children without identifiable risk factors. The goal of this study is to determine the incidence of truly community-acquired MRSA soft tissue infections in our community and geographically map regions of increased risk.
Methods:
After obtaining the institutional review board's approval, a retrospective chart review was conducted on 195 patients records who underwent an incision and drainage of soft tissue infections from January 1, 2000, to December 31, 2003. Thirteen patients were excluded from the study because no cultures were taken at the time of incision and drainage.
Results:
The most common organism isolated from wound culture was S aureus , 40% (73/182), of which 45% (33/73) were MRSA. Eighty-one percent (27/33) of MRSA infections were in Springfield, 1 of 18 towns represented in the patient population. Geographic information system analysis identified a significant MRSA cluster 1.96 km in diameter within the city of Springfield.
Conclusions:
Geography proved to be a significant risk factor for presenting with MRSA infection. Geographic maps of antibiotic resistance can be used to guide physician antibiotic selection before culture results are available. This has significant implications for the health care provider in proper antibiotic selection within the community.
Insights
Community-acquired methicillin-resistant Staphylococcus aureus (MRSA) soft tissue infections are increasing in children. Geographic mapping revealed a significant MRSA cluster in Springfield, identifying location as a key risk factor.
Area of Science:
- Pediatric infectious diseases
- Medical microbiology
- Public health epidemiology
Background:
- Community-acquired methicillin-resistant Staphylococcus aureus (MRSA) soft tissue infections present a growing health risk for children.
- An increase in MRSA infections among children without prior risk factors has been observed.
- This study aimed to determine the incidence and geographic distribution of community-acquired MRSA soft tissue infections.
Purpose of the Study:
- To ascertain the incidence of community-acquired MRSA soft tissue infections.
- To geographically map areas with a higher risk of MRSA infections.
- To identify geographic risk factors for MRSA infections in pediatric patients.
Main Methods:
- A retrospective chart review of 195 patients who underwent incision and drainage for soft tissue infections between January 2000 and December 2003.
- Exclusion of 13 patients due to lack of cultures taken during the procedure.
- Geographic Information System (GIS) analysis to map infection clusters.
Main Results:
- Staphylococcus aureus was the most common organism isolated (40%), with 45% of these being MRSA.
- The majority of MRSA infections (81%) were concentrated in Springfield, out of 18 represented towns.
- GIS analysis identified a significant MRSA cluster, 1.96 km in diameter, within Springfield.
Conclusions:
- Geographic location was identified as a significant risk factor for MRSA infection.
- Geographic maps of antibiotic resistance can aid physicians in early antibiotic selection.
- This data has critical implications for healthcare providers in community-based antibiotic prescribing practices.
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