Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Velocity storage in labyrinthine disorders.

T C Hain1, D S Zee

  • 1Department of Neurology, Northwestern University School of Medicine, Chicago, Illinois 60616.

Annals of the New York Academy of Sciences
|May 22, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preface.

Progress in brain research·2022
Same author

Consensus Paper: Neurophysiological Assessments of Ataxias in Daily Practice.

Cerebellum (London, England)·2018
Same author

Ocular stability and set-point adaptation.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2017
Same author

Eye movements in vestibular disorders.

Handbook of clinical neurology·2016
Same author

Mal de débarquement syndrome.

Handbook of clinical neurology·2016
Same author

The cerebellum in eye movement control: nystagmus, coordinate frames and disconjugacy.

Eye (London, England)·2015

Unilateral vestibular loss after acoustic neuroma removal significantly impairs the vestibulo-ocular reflex (VOR) and optokinetic nystagmus (OKAN) velocity storage. This suggests a complete loss of canal input storage but partial loss for visual input.

Area of Science:

  • Neuroscience
  • Ophthalmology
  • Otolaryngology

Background:

  • Vestibular disorders can arise from acoustic neuromas.
  • Vestibulo-ocular reflex (VOR) and optokinetic nystagmus (OKAN) are crucial for gaze stabilization.
  • Velocity storage integrates vestibular and visual signals for smooth eye movements.

Purpose of the Study:

  • To investigate the impact of unilateral peripheral vestibular lesions on VOR and OKAN.
  • To assess the velocity storage mechanism following acoustic neuroma removal.

Main Methods:

  • Studied 13 patients post-acoustic neuroma surgery.
  • Measured VOR and OKAN time constants and initial velocity.
  • Compared patient data to normal values.

Related Experiment Videos

Main Results:

  • Post-surgery VOR time constant was significantly reduced (6.4s vs. 18.5s normal).
  • Post-surgery OKAN time constant was also reduced (7.2s vs. 11.3s normal).
  • Mean initial OKAN velocity was slightly reduced (9.7deg/s vs. 11.7deg/s normal).

Conclusions:

  • Unilateral vestibular loss causes complete loss of velocity storage for canal input.
  • Partial loss of velocity storage for visual input was observed.
  • Findings align with current mathematical models of velocity storage.