Related Experiment Video
Updated: Aug 17, 2026
Acupuncture in a Rat Model of Asthma
Published on: August 25, 2020
The association between the DRD2 TaqI A polymorphism and smoking cessation in response to acupuncture in Koreans
Hi-Joon Park1, Seung-Tae Kim, Dong-Hak Yoon
1Department of Meridian and Acupuncture, College of Oriental Medicine, Kyung Hee University, Seoul, South Korea.
Objectives:
The response to acupuncture is presumed to differ with the individual; this variation might be due to genetic differences. Therefore, we examined whether the DRD2 TaqI A polymorphism is associated with the response to acupuncture in the treatment of smoking cessation in a Korean population.
Subjects:
A total of 231 healthy Korean male smokers participated in this study.
Interventions:
The subjects underwent three manual auricular acupuncture treatments in one week.
Design And Outcome Measures:
After 1 week, high and low responders to the acupuncture treatment were selected according to their cigarette consumption and the desire to smoke. A DRD2 TaqI A restriction enzyme fragment length polymorphism (RFLP) study examined genomic DNA extracted from blood samples.
Results:
The proportions of high, intermediate, and low responders were 28.6, 55.4, and 16.0%, respectively. The RFLP study showed that the distribution of the DRD2*A genotype and allele frequencies differed significantly between the high and low responders (chi(2) test, p = 0.031 and 0.016, respectively), and that high responders had a higher DRD2*A2 allele frequency than low responders.
Conclusions:
Our findings suggest that DRD2 TaqI A polymorphism is related to acupuncture response in smoking cessation treatment.
More Related Videos
03:05Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study
Published on: November 21, 2025
05:19A Preliminary Study on Warm Acupuncture and Moxibustion for Treating Chronic Obstructive Pulmonary Disease with Abdominal Distension
Published on: September 1, 2023