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Treatment of orbital myositis with adalimumab (Humira)
Alexa B Adams1, Michael Kazim, Thomas J A Lehman
1Division of Pediatric Rheumatology, Hospital for Special Surgery, New York, New York 10021, USA.
Abstract:
Adalimumab is a fully humanized IgG1 monoclonal antibody to tumor necrosis factor-a. We describe 2 patients (17 and 13 years of age) with refractory, steroid-dependent, recurrent nonspecific orbital myositis not controlled with standard immunosuppressive medications. Both improved with adalimumab treatment, allowing reduction in corticosteroid dosage without disease flare.
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