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[Protected mercaptoalkylpyrimidinones: synthesis and test for immunostimulating activity]
1Fakultät für Biowissenschaften der Universität Leipzig, Germany.
Die Pharmazie
|July 7, 2005
Abstract:
Protected mercaptoalkylpyrimidinones: synthesis and test for immunostimulating activity 3-Hydroxyalkyl-pyrimidine 1 reacts with phosphoroxychloride and thioglycolic acid or thiourea to yield pyrimidin-3-ylalkylthioacetic acids 3 or pyrimidin-3-ylalkylthiouroniumsalts 5 respectively. Some of the pyrimidines 3 and 5 showed immunomodulatory activity.
