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[Cystomanometric study of bladder sensation during sacral neuromodulation test]
François Leclers1, Eric Mourey, Jean Marie Galas
1Service d'Urologie, Hôpitaux de Brabois, Vandoeuvre les Nancy, France.
Summary
Sacral neuromodulation (SNM) improves bladder sensation in patients with overactive bladder. Increased bladder volume at first urge (B1) and urgency (B3) during cystometry predicts a positive response to SNM.
Area of Science:
- Urology
- Neuroscience
- Medical Engineering
Context:
- Hyperactive bladder (overactive bladder) affects millions globally, leading to significant quality of life impairment.
- Sacral neuromodulation (SNM) is an established treatment for overactive bladder, but predicting patient response remains a challenge.
Purpose:
- To evaluate how bladder sensation is modified during sacral neuromodulation (SNM) in patients with non-neurological hyperactive bladder.
- To correlate clinical outcomes with urodynamic findings during SNM testing.
Summary:
- A prospective study of 24 patients with hyperactive bladder undergoing SNM testing revealed that 42% showed significant symptom improvement (Group A).
- Group A patients demonstrated substantial increases in bladder capacity, volume at first urge (B1), and urgency (B3) during urodynamic assessment.
- Cystometry during SNM showed increased bladder volumes at B1 and/or B3 in all improved patients, unlike non-improved patients.
Impact:
- Findings suggest that increased bladder volume at B1 and B3 during cystometry can serve as a predictive criterion for selecting suitable candidates for SNM.
- This could optimize treatment selection and improve outcomes for patients with non-neurological hyperactive bladder.