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Updated: Aug 17, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
A novel technique to detect total occlusion in the right coronary artery using retrograde flow by transthoracic
Ryo Otsuka1, Hiroyuki Watanabe, Kumiko Hirata
1Department of Internal Medicine and Cardiology, Osaka City University Medical School, Japan.
Insights
Transthoracic Doppler echocardiography (TTDE) can detect reverse flow in the distal right coronary artery (d-RCA) and inferior septal branches (ISB). This noninvasive method accurately diagnoses occluded right coronary artery (RCA).
Area of Science:
- Cardiology
- Diagnostic Imaging
- Echocardiography
Background:
- Right coronary artery (RCA) occlusion diagnosis can be challenging.
- Noninvasive methods for detecting RCA occlusion are needed.
Purpose of the Study:
- To evaluate the utility of transthoracic Doppler echocardiography (TTDE) for diagnosing occluded right coronary artery (RCA).
- To assess the detection of reverse flow in the distal RCA (d-RCA) and inferior septal branches (ISB) as an indicator of RCA occlusion.
Main Methods:
- Coronary angiography and TTDE were performed on 129 patients.
- Antegrade and retrograde flow in the d-RCA and ISB were defined and assessed using TTDE.
Main Results:
- Retrograde flow was detected in 14 out of 18 patients with occluded RCA (11 in d-RCA, 3 in ISB).
- TTDE demonstrated 100% sensitivity and 97.8% specificity for identifying occluded RCA.
Conclusions:
- Detection of reverse flow in the d-RCA and ISB via TTDE is a valuable noninvasive diagnostic tool.
- TTDE offers a reliable method for diagnosing right coronary artery occlusion.
Background:
We hypothesized that detection of reverse flow in the distal right coronary artery (d-RCA) and the inferior septal branches (ISB) by transthoracic Doppler echocardiography (TTDE) would be useful for noninvasive diagnosis of the occluded right coronary artery (RCA).
Methods:
Coronary angiography and TTDE were performed on 129 patients. Antegrade flows in the d-RCA and the ISB were defined as directions from the base to the apex in the posterior sulcus and from anterior to inferior in the inferior septum, respectively. Retrograde flow was defined as an inverse direction.
Results:
Retrograde flow was obtained by TTDE in 14 patients (d-RCA:11, ISB:3) of 18 patients with occluded RCA. The sensitivity and the specificity for identification of occluded RCA were 100% and 97.8%, respectively.
Conclusion:
Detection of reverse flow in the d-RCA and the ISB using TTDE is a useful method for the noninvasive diagnosis of occluded RCA.
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