Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Quantum dots as cellular probes.

A Paul Alivisatos1, Weiwei Gu, Carolyn Larabell

  • 1Department of Chemistry, University of California, Berkeley, California 94720, USA. alivis@uclink4.berkeley.edu

Annual Review of Biomedical Engineering
|July 12, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

m6A-Modified KLF11 Inhibits Macrophage Foam Cell Formation by Transcriptionally Suppressing ATP5B Expression in Atherosclerosis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026
Same author

Visualizing Millisecond Atomic Dynamics of Nanocrystals in Liquid.

Journal of the American Chemical Society·2026
Same author

Emissive Colloidal GaAs Quantum Dots.

Journal of the American Chemical Society·2026
Same author

DFT investigation of the 2-aminothiazole-catalyzed five-component reaction of CO<sub>2</sub>/amines/aldehydes: multi-species synergistic activation and chemoselective control in <i>N</i>-methylation.

Organic & biomolecular chemistry·2026
Same author

Quantifying Photochemical Propulsion in Light-Powered Janus Micromotors.

ACS nano·2026
Same author

An investigation into the status of human milk feeding in very low birth weight infants: a multicenter study.

International breastfeeding journal·2026
Same journal

Physics-Informed Machine Learning in Biomedical Science and Engineering.

Annual review of biomedical engineering·2026
Same journal

Advancements and Challenges in Computer-Assisted Medical Interventions for Image-Guided Prostate Cancer Treatments.

Annual review of biomedical engineering·2026
Same journal

Recent Advances in mRNA Therapeutic Cancer Vaccines.

Annual review of biomedical engineering·2026
Same journal

Artificial Intelligence-Based Analysis of Laparoscopic Imaging for Intraoperative Surgical Decision Support.

Annual review of biomedical engineering·2026
Same journal

Viscoelasticity of the Heart: An Overview of Viscoelastic Measurements at Different Scales.

Annual review of biomedical engineering·2026
Same journal

Digital Twins for Biofluids.

Annual review of biomedical engineering·2026
See all related articles

Quantum dots (QDs) are bright semiconductor nanocrystal labels revolutionizing biological imaging. Recent advances enhance their cellular applications, showing great potential for in vitro and in vivo studies.

Area of Science:

  • Biotechnology
  • Nanotechnology
  • Cellular Imaging

Background:

  • Semiconductor nanocrystals, known as quantum dots (QDs), are highly fluorescent and stable light emitters.
  • Their adoption as fluorescent labels in biological applications has rapidly advanced in recent years.
  • Significant progress has been made in understanding QD surface chemistry, biocompatibility, and targeting capabilities.

Purpose of the Study:

  • To review recent advancements in the application of quantum dots (QDs) at the cellular level.
  • To highlight the potential of QDs as probes for various biological imaging techniques.
  • To discuss limitations and future prospects of QD-based probes.

Main Methods:

  • Literature review of recent studies on quantum dot applications in biology.

Related Experiment Videos

  • Analysis of advancements in QD surface chemistry and biocompatibility.
  • Evaluation of QD performance in cellular labeling and imaging techniques.

    • Main Results:

    • Quantum dots demonstrate significant potential as fluorescent probes for both in vitro and in vivo imaging.
    • Recent improvements have enhanced QD surface chemistry, biocompatibility, and targeting specificity.
    • QDs are effectively used in immunolabeling, cell tracking, in situ hybridization, and Förster Resonance Energy Transfer (FRET).

    Conclusions:

    • Quantum dots represent a powerful tool for cellular-level biological research and diagnostics.
    • Continued research into QD properties and applications will further expand their utility in biomedical imaging.
    • Addressing current limitations will unlock broader future applications for quantum dot probes.