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Published on: November 4, 2010
Treatment patterns for pediatric asthma prior to and after emergency department events
David A Stempel1, Trent P McLaughlin, Richard H Stanford
1Infomed Northwest, Bellevue, Washington, USA. econmed@msn.com
Insights
Pediatric asthma patients heavily rely on rescue inhalers. Emergency department visits for asthma lead to only a temporary increase in controller medication use, highlighting a need for better asthma management in children.
Area of Science:
- Pediatric Pulmonology
- Health Services Research
- Pharmacotherapy
Background:
- Asthma affects millions of children annually, with a significant burden on emergency departments (EDs).
- Understanding treatment patterns is crucial for improving pediatric asthma care and reducing ED utilization.
Purpose of the Study:
- To describe asthma treatment patterns in children during the year preceding and two months following an asthma-related ED event.
- To evaluate the impact of ED visits on the utilization of controller medications versus rescue inhalers.
Main Methods:
- Retrospective observational study using administrative claims data from a large US managed-care database.
- Inclusion criteria: children aged 1-17 with at least one asthma-related ED visit in 2001, with 12 months pre- and 2 months post-event data.
- Analysis of prescription dispensing patterns for inhaled corticosteroids (ICS), oral corticosteroids (OCS), and short-acting beta-agonists (SABAs).
Main Results:
- 5,501 pediatric asthma ED admissions were identified.
- In the year prior to ED visits, only 19.4% of children received ICS, while 58.3% received SABAs, with a high ratio of SABA to ICS dispensing.
- Following ED events, ICS and OCS prescriptions increased significantly in the first month but returned to near baseline levels by the second month.
Conclusions:
- Children with asthma exhibit a strong dependence on short-acting beta-agonists (rescue inhalers).
- Asthma-related ED events trigger only a short-lived increase in controller medication prescribing.
- Current treatment patterns suggest a need for enhanced asthma control strategies in pediatric populations to prevent recurrent ED visits.
Abstract:
There are 2 million asthma-related emergency department (ED) events each year in the United States. Children share a disproportional burden of these events. This study was designed to describe the treatment patterns in children in the year prior to and 2 months after an ED event. This retrospective observational study utilized the PharMetrics Integrated Outcomes Database that contains administrative claims from over 20 managed-care plans across the United States. Children aged 1-17 years with at least one ED visit for asthma during 2001 were included. Patients were required to have data available 12 months prior to and 2 months following the ED visit. We identified 5,501 pediatric asthma-related ED admissions. In the year prior to the ED event, 19.4% of children received an inhaled corticosteroid (ICS), 31.4% an oral corticosteroid (OCS), and 58.3% a short-acting beta-agonist (SABA). Overall, there were 3.7 albuterol units for every ICS unit dispensed in the 12 months prior to the event. Ninety-four percent of the children had an office visit in the year prior to the ED visit. Prescriptions dispensed for ICS and OCS increased 2.9-fold and 8.2-fold, respectively, in the month after the ED event. However, the dispensing rates for both medications reverted to near baseline by the second month after the index event. In conclusion, this study demonstrates the dependence of children with asthma on the use of rescue medications. An ED event results in only an incremental and transient increase in ICS-containing controller treatment.
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