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Early effect of exogenous Na hyaluronate on mucociliary clearance
Altan Yildirim1, Bulent Turgut, Ali Ihsan Bebek
1Medical Faculty, Department of Otorhinolaryngology Head and Neck Surgery, Cumhuriyet University Hospital, TR-58140 Sivas, Turkey.
Background:
An animal study is performed to determine the early effect of 1% Na hyaluronate on mucociliary clearance function.
Methods:
One percent of Na hyaluronate was introduced into the maxillary sinuses of rabbits by anterior antrostomy. A physiological solution of 1% NaCl was introduced into the maxillary sinuses of a control group to equalize the influence of Na for both groups. The treatment material was sprayed with an atomizer for coating the maxillary sinus lining. Technetium-99m diethylenetriamine pentaacetate dynamic scintigraphic imaging was performed to evaluate mucociliary clearance function on all rabbits 72 hours after the surgical procedure.
Results:
Although the mean rate of mucociliary clearance of the Na hyaluronate group was slightly worse than the control group; there was no statistically significant difference between them.
Conclusion:
There is no early effect of exogenous 1% Na hyaluronate on mucociliary clearance function.
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