Jove
Visualize
Contact Us

Related Experiment Videos

[Drug therapy for corneo-conjunctival neoplasm].

A Murcia López1, J Borrás Blasco, M C Alvarado Valero

  • 1Servicio de Oftalmología, Hospital General Universitario de Elche, Alicante, Spain.

Farmacia Hospitalaria : Organo Oficial De Expresion Cientifica De La Sociedad Espanola De Farmacia Hospitalaria
|July 15, 2005
PubMed
Summary

Interferon alpha 2b is a promising adjuvant therapy for corneo-conjunctival neoplasm, showing a 100% response rate and low adverse effects. Mitomycin C is effective but causes more side effects, while 5-fluorouracil is a less preferred option.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Concordance of medication prescription records in the hospitalised surgical patient].

Journal of healthcare quality research·2024
Same author

[The value of persistence in the 5P Medicine model for chronic diseases].

Journal of healthcare quality research·2023
Same author

Comparability of the Retinomax K-plus 3 handheld autorefractometer in quick mode versus on-table autorefractometer in standard mode.

Archivos de la Sociedad Espanola de Oftalmologia·2023
Same author

Repeatability and comparability of a new swept-source optical coherence tomographer in optical biometry.

Archivos de la Sociedad Espanola de Oftalmologia·2022
Same author

Limits of the precision in refractive results after cataract surgery.

Archivos de la Sociedad Espanola de Oftalmologia·2022
Same author

Posterior bilateral lens luxation in an agitated patient: Cause or consequence?

Archivos de la Sociedad Espanola de Oftalmologia·2020
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Area of Science:

  • Ophthalmology
  • Oncology
  • Pharmacology

Context:

  • Corneo-conjunctival neoplasms require effective adjuvant therapies to reduce high relapse rates post-resection.
  • Topical chemotherapies like mitomycin C, 5-fluorouracil, and interferon alpha 2b have been explored for adjuvant treatment.

Purpose:

  • To review and compare the clinical effectiveness of various topical drug therapies used as adjuvants for corneo-conjunctival neoplasm.

Summary:

  • A literature search (1966-2004) identified studies on 5-fluorouracil, mitomycin C, and interferon alpha 2b for ocular neoplasms.
  • Interferon alpha 2b demonstrated a 100% response rate with minimal adverse effects and a 4% relapse rate.
  • Mitomycin C showed a 90% response rate but with significant adverse events, while 5-fluorouracil had an 88% response rate and 20% relapse rate.

Related Experiment Videos

Impact:

  • Interferon alpha 2b emerges as a favorable option due to its high efficacy and favorable safety profile.
  • Mitomycin C is effective but limited by adverse events, and 5-fluorouracil is considered a secondary treatment option.