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Huge extracranial asymptomatic frontal invasive meningioma: a case report
Milan B Jovanovic1, Iva Berisavac, Jelena V Perovic
1Department of Otorhinolaryngology and Maxillofacial and Cervical Pathology, Clinical Hospital Centre Zemun, Belgrade, Serbia and Montenegro. majov@eunet.yu
Abstract:
Meningioma is a well-recognized tumor of the central nervous system, but it rarely appears as an extracranial tumor secondarily extended into the paranasal sinuses. Meningiomas arise from arachnoid cap cells that form the external membrane of the brain. Most meningiomas are slow growing and are usually not associated with substantial underlying brain edema; they cause symptoms by the compression of adjacent neural structures. An interesting natural history of a neglected meningioma with extracranial extension is described. The diagnosis of meningioma was established by CT imaging, finally based on the histopathology and immunochemistry. The meningioma cells in our male patient were positive for progesterone receptors. The patient underwent surgical treatment and recovered without complications. On follow-up 1 year later there were no signs of process expansion.
Insights
This case study details a rare extracranial meningioma extending into the paranasal sinuses. Surgical treatment led to a successful recovery with no recurrence observed after one year.
Area of Science:
- Neurology
- Oncology
- Pathology
Background:
- Meningiomas are central nervous system tumors originating from arachnoid cap cells.
- While typically intracranial, meningiomas can rarely present as extracranial tumors with paranasal sinus extension.
Observation:
- A case of a neglected meningioma with significant extracranial extension into the paranasal sinuses is presented.
- Diagnosis was confirmed via CT imaging, histopathology, and immunochemistry.
Findings:
- The meningioma cells were found to be positive for progesterone receptors.
- The patient, a male, underwent successful surgical resection.
Implications:
- This case highlights the importance of considering extracranial meningiomas in differential diagnoses for sinonasal masses.
- Complete surgical excision offers a favorable prognosis, as evidenced by the 1-year follow-up showing no signs of recurrence.