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A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
Advances in endovascular aneurysm treatment: are we making a difference?
Jeffrey M Katz1, Apostolos J Tsiouris, Alessandra Biondi
1Department of Neurology, New York Presbyterian Hospital-Weill Medical College of Cornell University, New York, NY 10021, USA.
Newer endovascular aneurysm repair technologies, including bioactive coils and intracranial stents, show high success rates for aneurysm occlusion. These advanced techniques offer safe and effective treatment options for complex aneurysms with minimal complications.
Area of Science:
- Neurosurgery
- Interventional Radiology
- Vascular Surgery
Background:
- Endovascular aneurysm repair (EVAR) has advanced with new devices like bioactive/expansile coils and intracranial stents.
- These innovations aim to improve aneurysm occlusion rates and long-term durability.
- Assessing outcomes of these newer technologies is crucial for clinical practice.
Purpose of the Study:
- To evaluate the immediate and midterm clinical and angiographic outcomes of endovascular aneurysm repair using novel technologies.
- To assess the safety and efficacy of bioactive coils and intracranial stents in treating a diverse range of aneurysms.
- To determine complication rates, recanalization, and retreatment rates associated with these advanced EVAR techniques.
Main Methods:
- Retrospective analysis of 134 patients with 142 aneurysms treated between 2001 and 2004.
- Independent neurological and neuroradiological review of clinical and angiographic data.
- Detailed analysis of device utilization, including Matrix coils, HydroCoils, and Neuroform stents.
Main Results:
- Total or subtotal angiographic occlusion achieved in 76% initially, increasing to 96% at last follow-up.
- Aneurysm recanalization occurred in 14%, with 18% requiring retreatment.
- Clinically relevant complications were 6.0%, with low procedure-related morbidity (0.6%) and mortality (0.6%) at 6 months.
Conclusions:
- Newer embolization technologies, including bioactive coils and stents, are effective for complex aneurysms.
- These advanced EVAR techniques demonstrate successful aneurysm occlusion with low morbidity and mortality.
- The study supports the successful application of novel endovascular devices in aneurysm treatment.
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