Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Measuring blood pressure in small laboratory animals.

Klaas Kramer1, René Remie

  • 1Department of Safety and Environmental Affairs (DVM), Free University, Amsterdam, The Netherlands.

Methods in Molecular Medicine
|July 21, 2005
PubMed
Summary

Radiotelemetry offers a more efficient and reliable method for monitoring blood pressure (BP) in rats and mice compared to traditional tail cuff or catheter techniques. This advanced approach overcomes the drawbacks of older methods for accurate BP measurements in awake animals.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recognition of pain and distress.

Laboratory animals·2026
Same author

Fit for Purpose Assessment: A New Direction for IACUCs.

ILAR journal·2022
Same author

Improved method for the catheterization of the right ventricle in a rat model of pulmonary artery hypertension.

Interactive cardiovascular and thoracic surgery·2020
Same author

Sufentanil-medetomidine anaesthesia compared with fentanyl/fluanisone-midazolam is associated with fewer ventricular arrhythmias and death during experimental myocardial infarction in rats and limits infarct size following reperfusion.

Laboratory animals·2017
Same author

Sex Differences in Physiological Acclimatization after Transfer in Wistar Rats.

Animals : an open access journal from MDPI·2015
Same author

Effects of Transfer from Breeding to Research Facility on the Welfare of Rats.

Animals : an open access journal from MDPI·2015

Area of Science:

  • Physiology
  • Surgical Techniques
  • Animal Models

Background:

  • Conventional methods like tail cuff and exteriorized catheters for monitoring blood pressure (BP) in rodents have significant drawbacks, limiting accuracy.
  • These traditional techniques are often labor-intensive and can be unreliable for obtaining precise BP measurements in conscious, freely moving animals.

Purpose of the Study:

  • To describe the surgical aspects of implantable radiotelemetry for monitoring blood pressure (BP) in awake rats and mice.
  • To highlight the advantages of radiotelemetry over conventional BP monitoring methods in laboratory animals.

Main Methods:

  • Implantable radiotelemetry devices for measuring physiological variables including electrocardiogram (ECG), heart rate (HR), and body temperature (BT) in freely moving rodents.
  • Surgical procedures for the implantation of radiotelemetry transmitters to enable continuous BP monitoring.

Related Experiment Videos

Main Results:

  • Radiotelemetry measurements of physiological variables are more efficient, reliable, and less labor-intensive than traditional methods.
  • Implantable radiotelemetry circumvents many problems associated with tail cuff and exteriorized catheter BP monitoring techniques in rats and mice.

Conclusions:

  • Implantable radiotelemetry is a validated and superior technique for measuring blood pressure in laboratory animals like rats and mice.
  • This method provides accurate and less invasive BP monitoring, overcoming limitations of conventional approaches.