Protoneus-sequence: extended fluid-attenuated inversion recovery MR imaging without and with contrast enhancement
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1Division of Neuroradiology, Department of Radiology, Medical University of Vienna, Währingergürtel 18-20, A-1090 Vienna, Austria. christian.nasel@perfusion.at
Abstract:
Fluid-attenuated inversion recovery imaging (=flair imaging) is widely used as primary screening sequence in various investigation protocols, due to its high lesion contrast and sensitivity in detection of parenchymatous and leptomeningeal disease. An additional increase of sensitivity for detection of lesions may be achieved by contrast-enhanced flair imaging. Based on flair imaging a dual-echo inversion recovery imaging sequence (=proton echo usage [=protoneus] - sequence) was developed, which could significantly extend the possibilities of conventional flair imaging.
Insights
Fluid-attenuated inversion recovery (FLAIR) imaging enhances lesion detection. A new dual-echo sequence, proton echo usage (PROTONEUS), further improves sensitivity for detecting brain and meningeal diseases.
Area of Science:
- Radiology
- Medical Imaging
- Neuroimaging
Background:
- Fluid-attenuated inversion recovery (FLAIR) imaging is a crucial MRI sequence for detecting parenchymal and leptomeningeal diseases.
- FLAIR imaging offers high lesion contrast and sensitivity, making it a primary screening tool in various diagnostic protocols.
- Contrast-enhanced FLAIR imaging can further augment lesion detection sensitivity.
Purpose of the Study:
- To introduce a novel dual-echo inversion recovery imaging sequence based on FLAIR.
- To evaluate the potential of this new sequence, termed proton echo usage (PROTONEUS), to extend conventional FLAIR imaging capabilities.
Main Methods:
- Development of a dual-echo inversion recovery sequence derived from FLAIR principles.
- The sequence is named proton echo usage (PROTONEUS).
Main Results:
- The PROTONEUS sequence was developed based on FLAIR imaging.
- This novel sequence has the potential to significantly expand the diagnostic possibilities offered by conventional FLAIR imaging.
Conclusions:
- The development of the PROTONEUS sequence represents an advancement in MRI techniques.
- This new sequence may offer enhanced capabilities for lesion detection beyond conventional FLAIR imaging.
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