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Intraocular pressure over the clinical range of blood pressure: blue mountains eye study findings
Paul Mitchell1, Anne J Lee, Jie Jin Wang
1Department of Ophthalmology, University of Sydney, Australia. paul_mitchell@wmi.usyd.edu.au
Purpose:
To quantify the relation of blood pressure (BP) and intraocular pressure (IOP) across the clinical range of BP in an older phakic population not using glaucoma medications.
Design:
Cross-sectional population-based study
Methods:
Seated BP and applanation IOP were measured, and their relation was assessed in regression models.
Results:
Mean IOP of the two eyes increased linearly from 14.3 mm Hg for systolic BP <110 mm Hg to 17.7 mm Hg for systolic BP > or =200 mm Hg, a 3.4-mm Hg excursion over this range. Mean IOP also increased from 15.2 mm Hg for diastolic BP <70 to 18.4 mm Hg for diastolic BP > or =120, a similar variance. There were no changes after age and multivariate adjustments for IOP or after excluding undiagnosed glaucoma cases.
Conclusion:
A 3-mm linear IOP increase over the clinical spectrum of BP levels was evident; this variance is greater than with most other systemic and ocular parameters.
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