Related Experiment Video
Updated: Aug 16, 2026
Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Assessment of coronary intima--media thickness by optical coherence tomography: comparison with intravascular
Teruyoshi Kume1, Takashi Akasaka, Takahiro Kawamoto
1Department of Cardiology, Kawasaki Medical School, Kurashiki, Japan. tteru@med.kawasaki-m.ac.jp
Background:
Optical coherence tomography (OCT) is a new imaging method. With a resolution of approximately 10-20 Em, which is approximately 10-fold higher than that of intravascular ultrasound (IVUS).
Methods And Results:
This study compared the coronary intima - media thickness (IMT) and the intimal thickness of 54 coronary arterial segments evaluated by histological examination with the results of OCT and IVUS. There was better agreement in IMT between OCT and histological examination than between IVUS and histological examination (r = 0.95, p < 0.001, mean difference = -0.01+/-0.07 mm for OCT; r = 0.88, p < 0.001, mean difference = -0.03+/-0.10 mm for IVUS). There was good agreement in the intimal thickness between OCT and histological examination (r = 0.98, p < 0.001, mean difference = 0.01+/-0.04 mm).
Conclusions:
IMT could be measured more accurately by OCT than IVUS. In addition, the intimal thickness could be evaluated by OCT and correlated well with the histological examination.
Related Concept Videos
01:25Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
01:28Imaging Studies for Cardiovascular System V: CT
01:21Imaging Studies for Cardiovascular System IV: CMRI