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Secretion of macrophage fusion factor (MFF) by schistosome egg granulomas maintained in vitro
A Rodriguez-Acosta1, M E Girón, I Aguilar
1Universidad Central de Venezuela, Instituto de Medicina Tropical, Caracas.
Scandinavian Journal of Immunology
|June 1, 1992
Abstract:
The schistosome granuloma cultured in vitro under antigenic specific and unspecific stimulation releases macrophage fusion factor (MFF) into the medium, adjusting the production dynamics to the spontaneous modulation model already described. These findings demonstrate the feasibility of studying granulomatous response in mammalian schistosomiasis utilizing an in vitro model of lymphokine granuloma secretion.