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Related Concept Videos

Qualitative Analysis03:46

Qualitative Analysis

For solutions containing mixtures of different cations, the identity of each cation can be determined by qualitative analysis. This technique involves a series of selective precipitations with different chemical reagents, each reaction producing a characteristic precipitate for a specific group of cations. Metal ions within a group are further separated by varying the pH, heating the mixture to redissolve a precipitate, or adding other reagents to form complex ions.
For instance, group IV...
Calmodulin-dependent Signaling01:16

Calmodulin-dependent Signaling

Calmodulin (CaM) is a calcium-binding protein in eukaryotes that controls various calcium-regulated cellular processes. It has four calcium-binding sites that bind calcium to form the calcium-calmodulin ( Ca2+-CaM) complex. GPCR stimulation increases the calcium levels in the cells that bind to CaM and induces a conformational change.
The Ca2+-CaM complex does not have enzymatic activity by itself. Instead, the complex binds downstream target proteins, including membrane proteins or enzymes,...
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Skeleton and Calcium Homeostasis01:21

Skeleton and Calcium Homeostasis

Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
Synthesis and Functions of Calcitonin00:51

Synthesis and Functions of Calcitonin

Calcitonin, a vital polypeptide hormone, regulates calcium levels within body fluids. It is released by the parafollicular cells, also known as C cells, situated in the follicular epithelium of the thyroid gland. Calcitonin responds to fluctuations in blood calcium levels and the influence of gastrointestinal hormones like gastrin and cholecystokinin.
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
The Parathyroid Glands00:59

The Parathyroid Glands

The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by producing...

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An In Ovo Model for Testing Insulin-mimetic Compounds
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[Allergenic activity of non-calcinated egg shell calcium].

Motohiro Ebisawa1, Hiroshi Tachimoto, Kaori Ikematsu

  • 1Division of Pediatric Allergy, National Hospital Organization, Sagamihara National Hospital. m-ebisawa@sagamihara-hosp.gr.jp

Arerugi = [Allergy]
|July 27, 2005
PubMed
Summary
This summary is machine-generated.

Non-calcinated egg shell calcium shows minimal allergenic activity, comparable to calcinated forms. This suggests safety for individuals with egg hypersensitivity, addressing concerns about egg allergen contamination.

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Area of Science:

  • Food science
  • Allergology
  • Biochemistry

Context:

  • Egg shell calcium is a popular dietary supplement.
  • Concerns exist regarding potential egg allergen contamination in non-calcinated forms.
  • Japanese regulations require origin labeling for non-calcinated egg shell calcium due to allergen concerns.

Purpose:

  • To assess the allergenic potential of non-calcinated egg shell calcium.
  • To evaluate the safety of non-calcinated egg shell calcium for individuals with egg hypersensitivity.

Summary:

  • In vitro methods (SDS-PAGE, Western blotting, ELISA) and a single-blind oral challenge with 6 egg-hypersensitive patients were used.
  • Non-calcinated egg shell calcium demonstrated negligible allergenic activity compared to egg white.
  • All patients with egg hypersensitivity tolerated the oral challenge, showing no adverse reactions.

Impact:

  • Provides evidence for the low allergenicity of non-calcinated egg shell calcium.
  • Supports the safe use of non-calcinated egg shell calcium as a dietary supplement.
  • May inform regulatory decisions regarding labeling requirements for egg shell calcium products.