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Updated: Aug 12, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
[Birth weight and familial smoking]
A Alonso Ojembarrena1, J Cano Fernández, A Girón Velasco
1Pediatría. Hospital Infantil Universitario Niño Jesús, Madrid, España.
Insights
Maternal smoking during pregnancy increases the risk of low birth weight (LBW) infants. Parental smoking cessation is crucial for preventing infant health complications and associated costs.
Area of Science:
- Pediatric Health
- Reproductive Health
- Public Health
Context:
- Maternal smoking is a significant risk factor for adverse pediatric outcomes.
- Low birth weight (LBW) is a critical indicator of infant health and development.
Purpose:
- To investigate the association between parental smoking and low birth weight (LBW) in infants.
- To determine the impact of maternal and paternal smoking on infant birth weight.
Summary:
- A retrospective case-control study analyzed data from 2370 infants. Maternal smoking during pregnancy yielded an odds ratio (OR) of 1.42 for LBW.
- Paternal smoking also showed an association with LBW (OR: 1.37). Gestational age was a significant predictive factor (OR: 0.585).
Impact:
- Findings underscore the importance of smoking prevention programs for both parents.
- Reducing parental smoking can mitigate numerous infant health complications with substantial medical, social, and economic costs.
Introduction:
Tobacco smoking during pregnancy is an important risk factor in the pediatric population and has been associated with an increase in low birth weight (LBW) infants.
Patients And Methods:
We carried out a retrospective case-control study of infants admitted to the Infants Department of the Hospital Universitario Infantil Niño Jesús in Madrid. Data from 2370 infants admitted to the hospital between 2002 and 2004 were collected.
Results:
The odds ratio (OR) for having a LBW infant was 1.42 (95 % CI: 1.017-1.985) among mothers who smoked during pregnancy and was 1.37 (95 % CI: 1.014-1.863) among women whose partners smoked. Gestational age was also a predictive factor of birth weight: the OR was 0.585 (95 % CI: 0.545-0.628). No significant differences for risk of LBW were found between sexes (OR: 1.25; 95 % CI: 0.934-1.671).
Conclusions:
Our results should reinforce the importance of smoking prevention during and after pregnancy in both parents, which could reduce many complications in children's health with a high medical, social and economic cost.
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