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Related Experiment Videos

Colon motility during a panic attack.

Paul E Hyman1, Jose Cocjin

  • 1Department of Pediatrics, University of Kansas School of Medicine, Kansas City, Kansas, USA. phyman@kumc.edu

Psychosomatic Medicine
|July 28, 2005
PubMed
Summary
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Panic attacks can trigger high amplitude propagating contractions in the colon, potentially explaining gastrointestinal distress and diarrhea in patients experiencing panic attacks.

Area of Science:

  • Gastroenterology
  • Psychosomatic Medicine
  • Neurogastroenterology

Background:

  • Colon manometry is a diagnostic tool for evaluating colon neuromuscular function and defecation disorders.
  • Understanding the link between psychological stress and gut motility is crucial for comprehensive patient care.

Observation:

  • A patient undergoing colon manometry experienced a panic attack during the procedure.
  • During the panic attack, a notable increase in colon motor activity was observed.

Findings:

  • The panic attack coincided with a series of 15 high amplitude propagating contractions over 45 minutes.
  • The frequency of these contractions decreased from 4 per 10 minutes to 1.5 per 10 minutes during the observation period.

Implications:

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  • These findings suggest a direct physiological link between panic attacks and abnormal colonic motility.
  • This may elucidate the pathophysiology of gastrointestinal symptoms like diarrhea in individuals with panic disorder.
  • Further research could explore targeted interventions for managing both panic symptoms and related gut issues.