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From SRY to SOX9: mammalian testis differentiation
Yoshiakira Kanai1, Ryuji Hiramatsu, Shogo Matoba
1Department of Veterinary Anatomy, The University of Tokyo, Yayoi 1-1-1, Tokyo 113-8657. aykanai@mail.ecc.u-tokyo.ac.jp
Journal of Biochemistry
|July 28, 2005
Summary
The sex-determining region Y (Sry) gene initiates male gonad development in mammals. This study explores how Sry and Sox9 gene expression drives early testis differentiation and associated cellular events.
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