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Molecular and classical cytogenetic analyses demonstrate an apomorphic reciprocal chromosomal translocation in
R Stanyon1, J Wienberg, D Romagno
1Istituto di Antropologia fisica, University of Genoa, Italy.
American Journal of Physical Anthropology
|June 1, 1992
Abstract:
The existence of an apomorphic reciprocal chromosomal translocation in the gorilla lineage has been asserted or denied by various cytogeneticists. We employed a new molecular cytogenetic strategy (chromosomal in situ suppression hybridization) combined with high-resolution banding, replication sequence analysis, and fluorochrome staining to demonstrate that a reciprocal translocation between ancestral chromosomes homologous to human chromosome 5 and 17 has indeed occurred.