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[The relationship between microalbuminuria and plasma high sensitivity C reactive protein]
Jiang-tao Yan1, Hui Ye, Dao-wen Wang
1Department of Internal Medicine, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Objective:
To investigate the relationship between microalbuminuria (MA) and plasma high sensitivity C reactive protein (hsCRP).
Method:
The plasma hsCRP level and urine albumin level of 746 Chinese people were detected with ELISA and analyzed, respectively.
Result:
The hsCRP level of MA group increased significantly compared with the control group (2.23 +/- 3.35 mg/L vs 1.68 +/- 2.58 mg/L, P < 0.05), the incidence of MA increased significantly when the plasma hsCRP level was beyond 0.77 mg/L (P < 0.05); logistic analysis showed that the occurrence of MA was associated with the plasma hsCRP level (OR = 1.153, P < 0.05).
Conclusion:
Increased plasma hsCRP was probably involved in the occurrence of MA, suggesting that inflammation may deteriorate endothelial dysfunction.
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