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Updated: Aug 16, 2026
Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
Published on: April 17, 2021
[Analysis of spontaneous reperfusion in acute myocardial infarction and its effect on short-term prognosis]
Song-biao Yan1, Hui Chen, San-qing Jia
1Heart and Blood Vessel Center, Beijing Friendship Hospital, Capital University of Medical Sciences, Beijing 100050, China.
Objective:
To analyse the clinical and angiographic characteristics of spontaneous reperfusion (SR) in AMI, and to evaluate its effect on short-term prognosis.
Methods:
112 consecutive AMI patients without intravenous thrombolytic therapy received emergent coronary angiography and primary PCI. The patients were divided into SR group (antegrade TIMI grade 2-3 flow) and non-SR group (antegrade TIMI grade 0-1 flow). The clinical, angiographic and prognostic features of the patients were analyzed.
Results:
31 patients (27.7%) were in SR group, and there was no significant difference in base-line clinical characteristics between the two groups. Compared with non-SR group, peak values of CK and CK-MB, Ventricular wall motion abnormality and mortality were lower in SR group, ejection fraction was higher in SR group. Logistic regression analysis showed that there was good correlation between SR and peak value of CK, collaterals, ventricular wall motion abnormality and pre-dilation in PCI.
Conclusion:
SR decreased infarction size, improved heart function and reduced 30-day mortality.
