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[Evolution and treatment of 19 cases of pertussis in infants under 4 months of age]

F Castillo Salinas1, E Soler Mir, U Aguilera Jacobsen

  • 1Servicio de Pediatría, Hospital Materno-Infantil Valle Hebron, Barcelona.

Anales Espanoles De Pediatria
|April 1, 1992
PubMed

Insights

Nineteen infants under four months experienced pertussis, a bacterial infection caused by Bordetella pertussis. Higher lymphocyte counts indicated severe illness, with common complications including pneumonia and recurrent cough.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Bacteriology

Context:

  • Pertussis (whooping cough) poses a significant threat to infants.
  • Early diagnosis and management are crucial for preventing severe outcomes.

Purpose:

  • To describe the clinical presentation, treatment, and outcomes of pertussis in infants under four months.
  • To identify factors associated with disease severity.

Summary:

  • Bordetella pertussis was identified in 19 infants under four months with characteristic symptoms like whooping cough, cyanosis, and feeding issues.
  • Treatment involved supportive care and antibiotics (josamycin), with salbutamol and beclomethasone also used.
  • Elevated lymphocyte counts (>40,000/mm2) correlated with increased illness severity.
  • Common complications included recurrent cough and pneumonia; no fatalities occurred.

Impact:

  • Highlights the severity of pertussis in young infants.
  • Informs clinical management strategies and emphasizes the importance of monitoring lymphocyte counts.
  • Underscores the need for effective preventive measures against pertussis in this vulnerable population.

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