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[Synthesis of metabolites and enantiomers of prolintane]
G Rücker1, M Neugebauer, D Zhong
1Pharmazeutisches Institut, Universität Bonn.
Archiv Der Pharmazie
|January 1, 1992
Abstract:
The synthesis of 15 possible metabolites of prolintane (1) (Katovit) which is used in the treatment of blood pressure disregulations is described. Furthermore, the preparation of the enantiomers of 1 is reported, starting with R-(+)- and S-(-)-phenylalaninol respectively.