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Updated: Aug 9, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
Treatment options and menopause regimens
1Menopause Unit, Monash Medical Centre, Clayton, Victoria.
Abstract:
Treating a woman with menopausal or perimenopausal problems is rewarding nd challenging, aided these days by the range of hormones, hormone combinations and delivery systems available. Keeping the following points in mind should improve treatment outcomes: Careful pretreatment assessment. Explanation of benefits and risks. Individualise therapy. Allow about 6 months to stabilise therapy. Regular follow up. Oestrogen only therapy for the woman with a uterus. Combined continuous oestrogen-progestogen therapy await further studies. Continue progestogen therapy for 2 to 3 years after ceasing implant therapy in a woman with a uterus. Severe side effects of progestogen may necessitate oestrogen-only therapy, with regular yearly endometrial biopsy. Duration of therapy is variable, but it may be long term for maximal prevention.
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