Related Experiment Video

Updated: Aug 16, 2026

Olfactory Assays for Mouse Models of Neurodegenerative Disease
07:27

Olfactory Assays for Mouse Models of Neurodegenerative Disease

Published on: August 25, 2014

Olfactory and auditory event-related potentials in Huntington's disease

Spencer Wetter1, Guerry Peavy, Mark Jacobson

  • 1Joint Doctoral Program in Clinical Psychology, San Diego State University, San Diego, CA 92120, USA.

Neuropsychology
|August 3, 2005
PubMed
Summary

Huntington's disease (HD) significantly delays olfactory processing, as measured by olfactory event-related potentials (OERPs). This olfactory deficit in HD is more pronounced than previously observed auditory processing delays.

More Related Videos

Assessment of Audio-Tactile Sensory Substitution Training in Participants with Profound Deafness Using the Event-Related Potential Technique11:39

Assessment of Audio-Tactile Sensory Substitution Training in Participants with Profound Deafness Using the Event-Related Potential Technique

Published on: September 7, 2022

Examining the Characteristics of Episodic Memory using Event-related Potentials in Patients with Alzheimer's Disease11:01

Examining the Characteristics of Episodic Memory using Event-related Potentials in Patients with Alzheimer's Disease

Published on: August 30, 2011

Related Concept Videos

Olfaction01:25

Olfaction

The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
Huntington Disease l: Introduction01:21

Huntington Disease l: Introduction

Huntington disease or HD is a progressive, fatal neurodegenerative disorder inherited in an autosomal dominant pattern.PathophysiologyIt is caused by expansion of the CAG trinucleotide repeat in the HTT gene on chromosome 4 (4p16.3), producing an abnormal huntingtin protein with an expanded polyglutamine tract. This misfolded protein disrupts cellular function, leading to neuronal death. Normal alleles have ≤26 repeats, 27–35 are intermediate (risk of expansion), 36–39 show reduced penetrance,...